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This work is licensed under a Creative Commons Attribution 4.0 International License.
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© Pragnya R. Donthineni, Dr., Somasheila I. Murthy, Joveeta Joseph, Prashant Garg, Manisha Acharya, Virender Sangwan, 2020
Affiliations
Pragnya R. Donthineni, Dr.
Cornea Service, L.V. Prasad Eye Institute, Hyderbad
Somasheila I. Murthy
Cornea Service, L.V. Prasad Eye Institute, Hyderbad
Joveeta Joseph
Jhaveri Microbiology Centre L V Prasad Eye Institute
Prashant Garg
Director, Kallam Anji Reddy Campus, L V Prasad Eye Insititute
Manisha Acharya
Cornea And Refractive Surgery Dept Dr Shroff’s Charity Eye Hospital
Virender Sangwan
Director, Innovations, Dr Shroff’s Charity Eye Hospital
How to Cite
Microsporidial stromal keratitis: an uncommon etiology of bilateral simultaneous corneal infection
- Pragnya R. Donthineni, Dr. ,
- Somasheila I. Murthy ,
- Joveeta Joseph ,
- Prashant Garg ,
- Manisha Acharya ,
- Virender Sangwan
Vol 17 No 3 (2020): Asian Journal of Ophthalmology
Submitted: Feb 22, 2020
Published: Dec 31, 2020
Abstract
We report three cases of bilateral microsporidial keratitis, which is an unusual presentation. All three patients presented with bilateral, simultaneous, asymmetrical, deep stromal corneal infiltrates with symptoms ranging from 5 to 12 months. Predisposing factors were noted in two of three patients. Corneal scrapings for microbiology and histopathology of corneal tissue revealed microsporidial spores from both eyes of all patients. There was no response to medical therapy and all underwent bilateral corneal transplantation. Case one additionally had recurrences in the graft and underwent repeat keratoplasties and eventually keratoprosthesis. Microsporidial stromal keratitis is a possible cause of keratitis in cases of very long-standing, indolent, culture-negative, deep stromal corneal infiltrates. So far, this infection has been reported as unilateral; however, we report these cases of bilateral infection, which is rare. Corneal transplantation is the preferred line of management due to lack of response to medical therapy.