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© Vidhya C., Kaushik Murali, Sowmya R., 2020
Sankara eye hospitals
Sankara eye hospitals, India
Sankara eye hospitals
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Safety and efficacy of reconstituted atropine 0.01% eye drops for Indian children with myopic progression
Vol 17 No 2 (2020): Asian Journal of Ophthalmology
Submitted: Sep 12, 2018
Published: Apr 30, 2020
Aim: To evaluate safety and efficacy of reconstituted atropine 0.01% eye drops for Indian children with myopic progression.
Methods: Fifty children with progressive myopia with their spherical equivalent increasing at least 0.75 D in 6 months (0.75 to 1.50 D) were put on reconstituted atropine 0.01%. Ocular examination, including near vision, near point of accommodation (NPA), pupil size and axial length, was done. Subjective symptoms of glare and photophobia were noted. Systemic side effects were documented. Analysis was done using Microsoft Excel 2010.
Results: The average age of patients was 9.5 years (range 5 to 14 years) and they were followed up for 1 year. Average mesopic and photopic pupil size was 5 and 4 mm, respectively. Average NPA was 9 cm. Mean increase in spherical equivalence was 0.18 D over 6 months. Average increase in axial length was 0.12 ± 0.11 mm over 6 months and 0.2 ± 0.29 mm over 1 year. Average increase in spherical equivalent over 6 months was 0.07 ± 0.19 D and over 1 year was 0.32 ± 0.29 D. No systemic side effects were recorded.
Conclusion: Reconstituted atropine 0.01% eye drops is safe and efficacious in slowing
the progression of myopia in Indian children.