2. Ramakrishnan R, Nirmalan PK, Krishnadas R, et al. Glaucoma in a rural population of Southern
India: The Aravind Comprehensive Eye Survey. Ophthalmology. 2003;110:1484-1490. doi:
3. McNaught AI, Allen JG, Healey DL, et al. Accuracy and Implications of a Reported Family History
of Glaucoma: Experience From the Glaucoma Inheritance Study in Tasmania. Arch Ophthalmol.
4. Leske MC, Nemesure B, He Q, Wu SY, Fielding Hejtmancik J, Hennis A. Patterns of open-angle
glaucoma in the Barbados Family Study. Ophthalmology. 2001;108(6):1015-1022.
5. Vegini F, Figueiroa Filho N, Lenci RF, Garcia Neto D, Susanna Junior R. prevalence of open angle
glaucoma in accompanying first degree relatives of patients with glaucoma. Clinics (Sao Paulo)
2008;63(3):329-332 doi: 10.15900/S1807-59322008000300007.
6. Nguyen RL, Raja SC, Traboulsi EI. Screening relatives of patients with familial chronic open angle
glaucoma. Ophthalmology. 2000;107(7):1294-1297.
7. Klein BE, Klein R, Sponsel WE, et al. Prevalence of glaucoma: The Beaver Dam Eye Study.
8. Wolfs RC, Klaver CC, Ramrattan RS, van Duijn CM, Hofman A, de Jong PT. Genetic risk of primary
open-angle glaucoma. Population-based familial aggregation study, Arch Ophthalmol.
9. Kong X, Zhu W, Chen X, Chen Y, Sun X. Familial aggregation of primary open angle glaucoma in
Shanghai, China. Mol Vis. 2013;19:1859-1865.
10. Rajendrababu S, Gupta N, Vijaykumar B, Kumaragurupari R, Krishnadas SR. Screening first
degree relatives of persons with primary open angle glaucoma in India. J Curr Glaucoma Pract.
11. Okeke CN, Friedman DS, Jampel HD, et al. Targeting Relatives of Patients With Primary Open
Angle Glaucoma: The Help the Family Glaucoma Project. J Glaucoma. 2007;16(6):549-555. doi:
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© Asian Journal of Ophthalmology, 2018
Vijaya Pai. H.
Kasturba Medical College, ManipalManipal University, Karnataka, India
How to Cite
Prevalence of glaucoma in first-degree relatives of patients with primary open-angle glaucoma and normal-tension glaucoma
Vol 16 No 2 (2018): Asian Journal of Ophthalmology
Submitted: Jul 30, 2016
Published: Nov 21, 2018
Objective: To determine the prevalence of glaucoma in first-degree relatives of patients with primary open-angle glaucoma (POAG) and normal tension glaucoma (NTG).
Methods: Observational study of first-degree relatives of patients with POAG and NTG who were screened for glaucoma.
Results: A total of 66 first-degree relatives of patients with glaucoma (POAG/NTG) were included in the study. We found a prevalence rate of 16.6%: 13.6% were diagnosed to have the disease and 3% were newly detected to have glaucoma during the study. We found that although 66.7% of the subjects were aware of the family history of glaucoma, only 36.4% were aware that they were at increased risk of developing glaucoma.
Conclusion: In our study, we found high prevalence of glaucoma in first-degree relatives of patients with glaucoma. This highlights the importance of selective screening of high-risk groups such as first-degree relatives of patients with POAG/NTG.